What is the only human disease to have been completely eradicated by vaccination? Answer
The only human disease up until now to have been completely eradicated by vaccination is smallpox.
This public health triumph was the result of a worldwide effort led by the World Health Organization (WHO) that took over a decade to achieve. The last naturally occurring case was reported in 1977, and three years later, in 1980, the WHO officially declared the disease eradicated. Today, the only known live samples of the smallpox virus are kept in two high-security laboratories in the United States and Russia.
Source:
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